Description of the DIAGNOSE CTE Research Project:

·       Developing methods to detect and diagnose chronic traumatic encephalopathy during life: rationale, design, and methodology for the DIAGNOSE CTE Research Project. Click here to read

Blood Tests and Cerebrospinal Fluid (CSF) Tests:

·       Examination of plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in former elite American football players. Click here to read

·       Inflammatory biomarkers for neurobehavioral dysregulation in former American football players: findings from the DIAGNOSE CTE Research Project. Click here to read

PET Scans:

·       Amyloid PET across the cognitive spectrum in former professional and college American football players: findings from the DIAGNOSE CTE Research Project. Click here to read

·       Associations between near end-of-life flortaucipir PET and postmortem CTE-related tau neuropathology in six former American football players. Click here to read

·       Flortaucipir tau PET findings from former professional and college American football players in the DIAGNOSE CTE research project. Click here to read

MRI Scans:

·       Brain morphometry in former American football players: Findings from the DIAGNOSE CTE research project. Click here to read

·       White matter hyperintensities in former American football players. Click here to read

·       Association of vascular risk factors and CSF and imaging biomarkers with white matter hyperintensities in former American football players. Click here to read

·       Cavum septum pellucidum in former American football players: Findings from the DIAGNOSE CTE Research Project. Click here to read

·       Repetitive head impacts and perivascular space volume in former American football players. Click here to read

Clinical Topics:

·       National Institute of Neurological Disorders and Stroke Consensus Diagnostic Criteria for Traumatic Encephalopathy Syndrome. Click here to read

·       Neuropsychological test performance of former American football players. Click here to read

·       Characterizing neurobehavioral dysregulation in former American football players: Findings from the DIAGNOSE CTE Research Project. Click here to read

·       Examination of parkinsonism in former elite American football players. Click here to read

·       Clinical outcomes and tau pathology in retired football players: Associations with diagnosed and witnessed sleep apnea. Click here to read