Dr. Alosco has published extensively in the fields of Alzheimer’s disease and related dementias, including CTE, and he is the PI of multiple NIH-funded grants. His research has set the stage for biomarker discovery in CTE and the long-term effects of repetitive head impacts on the white matter, and he has made major contributions to plasma biomarker development and validation in Alzheimer’s disease. He has written numerous book chapters, and he is the co-Editor of the Oxford Handbook of Adult Cognitive Disorders which was published by Oxford University Press in 2019.

He is the Project Lead of a multisite NIH/NINDS-funded U54 that is examining the late neuropathologies of exposure to repetitive head impacts and TBI and resulting clinical syndromes. He oversees studies on risk factors and clinicopathological correlations of CTE.

Dr. Alosco leads several NIH-funded human subject studies devoted to biomarker development for CTE and the long-term effects of repetitive head impacts on the white matter and vasculature.

A major focus of Dr. Stern’s research involves the long-term effects of repetitive brain trauma in athletes, including the neurodegenerative disease, CTE. He has been funded from NIH and the Department of Defense for his work on developing methods of detecting and diagnosing CTE during life, as well as examining potential genetic and other risk factors for this disease. He is the lead principal investigator for the 7-year, multi-center DIAGNOSE CTE Research Project, funded by the National Institute of Neurological Disorders and Stroke. The goal of DIAGNOSE-I was to develop methods of detecting and diagnosing CTE during life, including the development and examination of neuroimaging and fluid biomarkers, establishing and validating diagnostic criteria for Traumatic Encephalopathy Syndrome (TES), and studying potential risk factors of the disease. He is also the principal investigator of the new, NIH-funded Head Impact and Trauma Surveillance Study (HITSS). HITSS will involve annual (completely online) assessments of 2400 former soccer players (women and men) and 2400 former American football players, all age 40 or older, who played their sport at any level (from youth to pro), to examine repetitive head impact exposure and other risk factors for later-life cognitive, mood, and behavioral problems. His other major areas of funded research include the assessment and treatment of Alzheimer’s disease, the cognitive effects of chemotherapy in the elderly, thyroid-brain relationships, and driving and dementia. He is the BU site principal investigator for several clinical trials for the prevention and treatment of Alzheimer’s disease. Dr. Stern has also published on various aspects of cognitive assessment and is the senior author of many widely used neuropsychological tests, including the Neuropsychological Assessment Battery (NAB).

Dr. Stern has received several NIH and other national grants, has published over 250 journal articles, chapters, and abstracts, and is the co-editor of two published books: Sports Neurology, which is part of the Handbook in Clinical Neurology series published by Elsevier, and The Oxford Handbook of Adult Cognitive Disorders, which is part of the Oxford Handbook collection. He is a Fellow of both the American Neuropsychiatric Association and the National Academy of Neuropsychology. He has been a member of the Mackey-White Health and Safety Committee of the NFL Players Association, as well as the court-appointed Medical Scientific Committee for the NCAA Student-Athlete Concussion Injury Litigation. Dr. Stern has testified before the US Senate Special Committee on Aging and the US Senate Committee on Commerce, Science, and Transportation. He appears frequently in national and international print and broadcast media for his work on CTE and AD. He also appears in the feature length documentaries, “League of Denial” (PBS Frontline, 2013), “Head Games” (2012), and “I Remember Better When I Paint” (2009).